electrospun fibers SEM

ELECTROSPINNING MACHINES

Unparalleled precision, consistency, & flexibility

VIVOLTA’s EC-CLI R&D electrospinning system is our premier electrospinning machine for precise, climate-controlled nanofiber production. It is the same platform we rely on in our own medical electrospinning development and manufacturing, helping partners bring next-generation electrospun medical devices and materials to life.

With built-in climate control, modular hardware and advanced automation, EC-CLI is designed to make electrospinning more consistent, reproducible and scalable for demanding research teams.

Since 2008, our team has supplied high-quality electrospinning machines to leading universities, research institutes and medical device developers worldwide – first as IME, and now as VIVOLTA.

WHAT you can expect

EC-CLI: the electrospinning machine for nanofiber creation

With EC-CLI, you can expect:

The EC-CLI is the centerpiece of VIVOLTA’s electrospinning platform – the electrospinning machine at the heart of our contract development and manufacturing workflows.

It is designed to solve a common challenge in electrospinning labs: moving from “interesting results” to repeatable, publication- and product-ready data.

Controlled Environment

Stable, climate-controlled spinning conditions for reproducible results

Morphology Consistency

Consistent fiber morphology and scaffold thickness

Accelerated Development

Faster process development with less trial-and-error

Seamless Scale-Up

Easier transfer of parameters into larger-scale systems

Modular Flexibility

Flexible, modular design for customizable processes and versatile applications

Advanced R&D

Best-in-class professional-grade R&D system for the most challenging R&D projects

System Highlights

Electrospinning machines designed for performance

Fully integrated climate control

High-quality electrospinning starts with a stable environment. EC-CLI’s fully integrated climate control comes standard on every system – there is no need for a separate climate chamber.

  • Temperature range: 20–45 °C (±0.5 °C)
  • Humidity range: 10–80% RH (±2%)
  • Fast stabilisation: temperature typically in 10–40 minutes, humidity in minutes

Independent sensors inside the spinning chamber continuously compare actual values to setpoints, keeping your process stable even during long experiments.

Sterile cleanroom manufacturing process.

Product & process development

The EC-CLI electrospinning machine is built on a modular design, so you can configure it around your research instead of adapting your experiments to the hardware.

You can configure, for example:

Many of these modules are part of our dedicated Electrospinning Equipment range and can be added over time as your program grows.

High-Voltage Control

High-voltage configurations (standard positive nozzle / negative collector)

Multi-Nozzle Systems

Multiple translating nozzle stages and multi-nozzle options

Advanced Collectors

Flat, rotating and custom collectors – including low-temperature and spoke collectors

Process Enhancements

Optional HEPA filtration, gas shielding, real-time thickness measurement and anti-statics

Looking for add-on modules and collectors?
Explore our Electrospinning Equipment page to see compatible modules for EC-CLI.

Electrospinning Equipment & Add-On Modules (EC-CLI)

Versatility in forms & architectures

With EC-CLI, you can create a wide range of electrospun structures:

  • Flat meshes and membranes
  • Tubes and hollow cylinders
  • 3D shapes and more complex geometries

Independent control of nozzle and collector stages, plus co- and coaxial spinning options, make it possible to engineer complex fiber architectures tailored to your application.

 

Voltage configuration & process stability

EC-CLI uses a standard positive nozzle / negative collector configuration, with:

  • Up to +25 kV at the nozzle
  • Up to −10 kV at the collector

Built-in voltage ramp functionality improves process stability when producing thicker scaffolds or running long experiments, helping you maintain reproducible results from run to run.

Precision robotic assembly of medical components.

User-friendly interface & compact footprint

The EC-CLI system is designed to fit smoothly into busy labs:

  • Full-color touch screen with intuitive interface
  • Clear, guided workflows for setup and operation
  • Compact footprint that offers a generous working volume while saving lab space compared to larger systems

 

Automation, monitoring & data logging

To reduce manual variability and support robust documentation, the EC-CLI electrospinning machine includes:

  • Real-time process monitoring
  • Data logging of critical parameters
  • Programmable functions for more automated, repeatable runs

This helps your team document conditions precisely and speeds up process optimization.

Safety & environmental controls

Safety and environmental control are built into the machine architecture:

  • Integrated fume hood and controlled exhaust
  • Safety door switch voltage shut-off
  • 6-stage reverse osmosis (RO) water treatment system with UV light, providing high-purity water for the electrospinning process.
  • Options for HEPA filtration and medical-grade production

These features help maintain a clean, safe working environment that meets institutional requirements for solvent handling and particle control.

Built for advanced electrospinning applications

EC-CLI electrospinning machines are used across a wide range of application areas, including:

  • Medical devices & implants
  • Tissue engineering scaffolds
  • Drug delivery (including drug-eluting constructs)
  • Advanced wound care dressings
  • Filtration and separation
  • Energy storage (batteries, supercapacitors, fuel cells)
  • Performance textiles & protective materials

Because the same platform is used inside VIVOLTA’s own CDMO operations, the EC-CLI is well aligned with requirements for regulated medical device development and manufacturing.

A super zoomed in microfiber shard
A super zoomed in microfiber shard
FEATURES AND BENEFITS

The most complete R&D electrospinning machines & equipment available

Fully Integrated Climate Control

The EC-CLI machine’s fully-integrated climate control technology sets it apart, giving you ultimate control of your research. While other systems rely on additional modules, VIVOLTA’s climate control unit comes standard on all EC-CLI systems, because high-quality, reproducible electrospinning requires it.

  • Independent Control: Temperature and humidity are independently controlled via digital set-points, allowing for a wide range of processing conditions with industry-leading precision.
  • Quick Settling Times: The system can stabilize temperature within 10 to 40 minutes and humidity in less than 5 minutes, ensuring minimal downtime and efficient operation.
  • Closed Sensing/Feedback Loops: Independent spinning cabinet sensors verify actual temperature and humidity values in real-time versus target setpoints, maintaining setpoint stability even over long experiments.

 

Advanced Functionality

The EC-CLI electrospinning machine and add-on equipment offers advanced functionality to meet the most demanding research needs. A wide range of plug-&-play modules seamlessly integrate with the core system taking your research to the next level.

  • Gas-shielding: gaseous solvent vapor colocalized at the spinneret maintains a stable spinning environment and defect-free fibers for long experiments.
  • Anti-statics: reset the static charge buildup on the electrospinning equipment during long or sequential experiments to ensure consistent results from the start to the end of the day.
  • Real-time thickness measurement: patent-protected optical thickness measurement probes mesh thickness in real-time eliminating spin-for-time process variability.
  • Multi-component systems: small mandrels for small blood vessels, larger drums for ~A4 size meshes, specialty low temperature drums for higher porosity, and parallel spoke drums for aligned fibers.

 

Process Automation

Enhance efficiency and reduce human error with the EC-CLI system’s advanced process automation features. Real-time monitoring and comprehensive data logging capabilities enable precise tracking and analysis of your experiments. Programmable “teach in” functions allow you to automate processes, ensuring consistent and reliable results with minimal manual intervention.

  • Real-Time Monitoring and Data Logging: Track and analyze experiments with precision through real-time monitoring and comprehensive data logging capabilities.
  • Programmable Functions: Automate processes to enhance efficiency and reduce the potential for human error.

Precision laser cutting process.

 

User-Friendly Design

Experience intuitive operation with the EC-CLI system’s full-color touch panel and user-friendly interface. Designed for ease of use, the EC-CLI system requires minimal setup time, allowing researchers to start their experiments quickly and efficiently. Whether you are new to electrospinning technology or an experienced user, the EC-CLI system’s interface simplifies the process, making it accessible to all.

  • Intuitive Operation: The full-color touch panel and intuitive user interface make the EC-CLI system easy to operate, even for users new to electrospinning technology.
  • Minimal Setup Time: Designed for quick and easy setup, allowing researchers to start their experiments without extensive preparation.

 

Safety and Environmental Controls

Ensuring the safety of researchers and maintaining a clean working environment are paramount with the VIVOLTA EC-CLI electrospinning machine and add-on equipment. The CLI’s safety and environmental control features ensure that your research is conducted in a safe and clean setting.

  • Safety: The system includes a protective door switch and options for different high voltage configurations to ensure safe operation.
  • Clean Environment: The EC-CLI system can be equipped with an integrated fume hood and HEPA filters to minimize volatile solvent particulate and maintain a clean and safe working environment.

 

High-Quality Construction and Components

Constructed with high-quality materials and durable components, the EC-CLI electrospinning machine and add-on equipment ensures long-term reliability and performance.

  • Durable Build: Constructed with high-quality materials and components, ensuring long-term dependability and performance.
  • Advanced Water Treatment: Includes a 6-stage reverse osmosis (RO) water treatment system with UV light, providing high-purity water for the electrospinning process.
scanning electron micrograph of nanofibers made by electrospinning
microscope image of nanofibers made by electrospinning
scanning electron micrograph of nanofibers made by electrospinning
microscope image of nanofibers made by electrospinning
microscope image of nanofibers made by electrospinning
EC-CLI machine

From lab R&D to scalable electrospinning

  • VIVOLTA’s MediSpin™ systems for tubular manufacturing
  • Our ISO 13485-certified cleanroom environment for clinical and commercial production

This helps teams reduce scale-up risk and move faster from promising early results to validated processes.

summary of specifications

Technical highlights at a glance

A summary of key EC-CLI electrospinning machine specifications and capabilities:

Climate control

20–45 °C, 10–80% RH with tight tolerances.

Integrated Safety

Integrated fume hood and safety interlocks.

Configurable Voltage

Configurable voltage and multi-nozzle options.

Advanced Collectors

Flat and rotating collectors, with custom geometries possible.

Real-Time Measurement

Optional real-time thickness measurement module.

Process Automation

Data logging and process automation features.

Compact Footprint

Compact laboratory footprint with large working volume

Full list of specifications

Download a brochure

A super zoomed in microfiber shard
A super zoomed in microfiber shard
Working with us

Service, training & support

Investing in an electrospinning machine is only the first step – how you use it matters just as much.

VIVOLTA supports EC-CLI users with:

User Training

On-site or remote training for new and experienced users

Application Consulting

Application consulting to help design and optimise experiments

Global Support

Global service and maintenance support including the US, Canada, Europe, Australia, Japan, China, and Korea

Expert Access

Ongoing access to our electrospinning specialists for technical questions and process guidance

A super zoomed in microfiber shard
A super zoomed in microfiber shard
Next steps

Ready to get started with EC-CLI?

Researcher holding electrospinning product

Request a consultation

discuss your application with our electrospinning specialists.

Electrospinning vacancies

Download a brochure

See the EC-CLI brochure for full specifications and configuration options

Configure your EC-CLI system by combining the electrospinning machine with our dedicated electrospinning equipment and add-on modules.

PDF Donwload

"*" indicates required fields

You're almost there

Fill in the following to receive the PDF in your inbox:

Name*